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What is Retin-A-Gel?

Retin-A-Gel is used to treat acne. Tretinoin gel belongs to a group of medications called retinoids. Retinoids are used to treat psoriasis, skin aging, acne, and some cancers. These medications work by affecting the growth of skin cells. Tretinoin works by decreasing the number and severity of acne and pimples and promotes the healing of pimples that do develop. Acne is a very common skin condition that develops when oil and skin cells clog hair follicles.

Always take Retin-A as directed by the doctor. Follow all instructions closely.

  • Use tretinoin gel on the skin only. Keep out of your mouth, nose, and eyes. Do not take Retin-A by mouth. Rinse well with water if it ends up in any of these areas.
  • Wash your hands before and after use.
  • Wash affected skin and pat dry.
  • Put a thin layer on the affected skin and rub in gently.
  • Put it on at bedtime.
  • It may take 8-12 weeks to notice the results from this medication.


It is rare, but some people can have a very bad reaction to Retin-A. Tell your doctor if you have signs of an allergic reaction. Allergic reactions can include:

  • Hives, rash, swollen or blistered skin
  • Wheezing, tightness in the chest or throat
  • Swelling in the mouth, face, lips, tongue, or throat

Some weather conditions may irritate the skin. You may also make-up unless your doctor advises you not to. It is important to clean off all cosmetics before applying Retin-A.

You may get sunburned more easily, so avoid sunlamps and tanning beds. Use sunscreen and protective eyewear that protects you from the sun. Store your medication at room temperature and protect it from heat or open flame.

This medicine may cause harm to an unborn baby if you take it while pregnant. Tell your doctor right away if you become pregnant while taking Retin-A.

Side Effects of Retin-A

Some common side effects of Retin-A include but are not limited to:

  • Lightening of normal skin color
  • Burning, itching, scaling of the skin

Tell your doctor if you experience the following:

  • Feeling of warmth
  • Burning or stinging
  • Change in color of skin
  • Skin reactions like dry skin, redness, swelling, blisters, and peeling


What do I tell my doctor before taking Retin-A?

You should tell your doctor of any allergies to drugs, food, or substances. If you have any skin allergies you should let your doctor know.

Tell your doctor if:

  • Your skin is sunburned or sensitive to light.
  • You are taking drugs that make your skin more sensitive to light.
  • You are pregnant.

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