Glucophage XR (Metformin) belongs to a group of medications called biguanides. This medication works by reducing the amount of glucose made by the liver and by making it easier for glucose to enter into the tissues of the body. Metformin helps in controlling the amount of glucose (sugar) in your blood. This medicine helps decreasing the amount of glucose you absorb from food and the amount of glucose made by your liver. Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. Metformin is used to treat type 2 diabetes alone or sometimes along with Insulin or other medications. Glucophage XR is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medication is not used to treat type 1 diabetes.

Doctor's prescription is required to use this medicine.

Always use Glucophage XR (Metformin) as directed by your physician.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Ask your doctor if you have any questions.

Glucophage XR (Metformin) comes as a tablet to take by mouth. Take Glucophage XR with a meal, unless your doctor tells you otherwise. Take this medicine at around the same time every day. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Do not stop taking metformin without talking to your doctor.

Do not take this medicine in larger or smaller amounts or for longer than recommended.

Always take Glucophage XR (Metformin) exactly as directed by your doctor.

Before using Latuda, tell your doctor or pharmacist if you are allergic to it or any other medications. Tell your doctor or pharmacist about your medical history. Tell your doctor about all the other prescription and nonprescription medications you are taking.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

If you are going to need surgery, a MRI, CT scan, or other procedure, tell your doctor that you are taking this medicine. You may need to stop taking this medicine before the procedure.

Tell your doctor if you have ever had:

• kidney disease (your kidney function may need to be checked before you take this medicine);

• high ketone levels in your blood or urine;

• heart disease, congestive heart failure;

• liver disease; or

• if you also use insulin, or other oral diabetes medications.

Follow your doctor's instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Tell your doctor if you become pregnant while taking Glucophage XR.

You should not breastfeed while using this medicine.

Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.

Glucophage XR should not be given to a child younger than 10 years old.

NOTE: This medicine is only for you. Do not share this medicine with others.

Side effects that you should report to your doctor or health care professional as soon as possible:

-Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-Breathing problems
-Feeling faint or lightheaded, falls
-Muscle aches or pains
-Signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
-Slow or irregular heartbeat
-Unusual stomach pain or discomfort
-Unusually tired or weak

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-Diarrhea
-Headache
-Heartburn
-Metallic taste in mouth
-Nausea
-Stomach gas, upset

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What happens if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line. An overdose can cause severe hypoglycemia or lactic acidosis.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature. Protect from moisture and light.

Throw away any unused medicine after the expiration date.

What should I avoid while taking this medication?

Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.