Pentasa is a medication used to treat bowel diseases like ulcerative colitis. It helps to reduce the symptoms of diarrhea, rectal bleeding, and stomach pain. Mesalamine is part of the aminosalicylates, which work by decreasing swelling in the colon.

This medication is taken by mouth, usually 4 times a day. The dosage and frequency of this medication will depend on your ulcerative colitis and the direction of your doctor. Pentasa comes in the form of tablets and you should take it with meals.

• Swallow the medication whole. Do not crush, chew, or break.
• If you have trouble swallowing the pill, you can open the capsule and sprinkle it on applesauce or yogurt before you take it. Swallow this mixture right away.
• Take this medication at the same time each day.

Before taking this medication, tell your doctor:

• If you are allergic to aminosalicylates, salicylates, or if you have other allergies
• If you have a medical history of kidney disease, liver disease, stomach blockage, or skin problems

This medication can be taken during pregnancy if the patient clearly needs it. This medication also passes into the breast milk and could have negative effects on a nursing infant. Always discuss the risks and benefits with your doctor.

This drug is similar to aspirin and children taking Pentasa should not take it if they have recently received a vaccine. In these cases taking aspirin can increase a child’s risk of Reye’s syndrome.

Some common side effects of Pentasa may include:

• Diarrhea
• Headache
• Nausea
• Vomiting

Tell your doctor right away if you experience:

• Signs of kidney problems (change in urine)
• Dark urine
• Severe stomach pain
• Yellowing of the skin and eyes
• Severe dizziness

What should I avoid while taking Pentasa?

Ask your doctor before taking an antacid along with Pentasa. Some antacids have the ability to decrease the efficiency of Pentasa.

How do I store Pentasa?

Store the medicine in a closed container at room temperature away from heat, moisture, and direct light. Keep from freezing. Keep out of reach of children.