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What is Rybelsus?

Rybelsus (semaglutide) is an oral medication that belongs to a class of drugs called GLP-1 receptor agonists. By mimicking the actions of the natural hormone GLP-1, Rybelsus helps regulate blood sugar levels in individuals diagnosed with type 2 diabetes mellitus. To maximize the effects of Rybelsus, it’s important to take it alongside proper diet and exercise. [1] 


  1. [1]  FDA RYBELSUS®
  1. Take Rybelsus exactly as prescribed by your healthcare provider.
  2. Swallow the tablet with a maximum of 4 ounces of water at least 30 minutes before the first oral medications, food, and drink of the day. 
  3. Do not chew, crush, or cut the tablet.
  4. If you forget to take a dose, skip the missed dose, and resume your regular dosing the following day.
  5. It is important to maintain a healthy lifestyle, including a balanced diet and regular exercise, alongside Rybelsus for optimal results. [1]


  1. [1]  FDA RYBELSUS®


Before starting Rybelsus, consult with your physician about your medical history, including any instances of pancreatitis or diabetic retinopathy. Also, inform your healthcare provider about all the medications you are taking, as they may interact with Rybelsus. 

Do not take Rybelsus if you are planning a pregnancy in the next two months, are currently pregnant, or are breastfeeding. [1]


  1. [1]  FDA RYBELSUS®

Side Effects

Common side effects include:

  • Nausea
  • Abdominal pain
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation [1]

Serious side effects may occur in rare instances:

  • Pancreatitis 
  • Diabetic retinopathy
  • Hypoglycemia
  • Acute Kidney Injury
  • Hypersensitivity [1]

If you experience any serious or persistent side effects, please contact your healthcare provider so they can provide you with the best course of action.


  1. [1]  FDA RYBELSUS®


What if I miss a dose?

If you miss a dose of Rybelsus, skip the missed dose for that day. Continue with your regular dosing schedule the next day. [1]

How should I store Rybelsus?

Rybelsus should be stored in a dry place at room temperature (68oF -77oF). 

Tablets should be stored inside the Rybelsus bottle, not in a pill organizer or external storage. The blue Rybelsus bottle cap contains a drying agent that protects the tablets from moisture. [2]

What happens if I don’t take Rybelsus on an empty stomach?

If Rybelsus is not taken on an empty stomach, or if you wait less than 30 minutes to consume food or beverages after taking Rybelsus, the absorption of the medication will decrease, and its effects will lessen. Therefore, adhering to the recommended guidelines is crucial to ensure the maximum benefits of Rybelsus are achieved. [1]

How often do I need to take Rybelsus?

Rybelsus should be taken once a day, at the same time every day. To achieve maximum benefits from Rybelsus, take Rybelsus on an empty stomach. Avoid eating, drinking, and taking other oral medications for at least 30 minutes after taking Rybelsus. A sip of water up to 4 ounces is allowed to assist in swallowing the tablet. [1]


  1. [1]  FDA RYBELSUS®
  2. [2]  novoMEDLINK Rybelsus® (semaglutide) dosing guide and schedule

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October 26, 2022

Delivery was great!

Lin C

October 13, 2022

You have always been exemplary in service.

Gerald W

October 8, 2022

Excellent service. For instance, calling my doctor directly for prescription renewal is much appreciated and smooths out the order process. They have always shipped on time even during the major Covid 19 scare. Their representatives are always pleasant and helpful. All in all, a good experience.

Rick P

October 7, 2022

I am extremely pleased with the promptness of always getting back with me always & have not had any problems at all. The only complaint I have is there is no price on the invoice I receive or the date it will be withdrawn from my checking account. This would be extremely helpful to me. Overall I am very pleased with your service!!

Bertha W

October 6, 2022

I really appreciated the help in walking me through how to submit my prescriptions and keeping me informed on shipment. I am telling my friends who need this service to get their meds to call you.

Sandra C

October 5, 2022

The contact person was so nice and explained everything so that I understood. So thankful for this pharmacy. My husband and I are on a very expensive med and it’s unaffordable in the US but is affordable thru this pharmacy.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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