Tradjenta (Linagliptin) belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. Tradjenta (Linagliptin) helps lowering blood sugar levels in patients with type 2 diabetes. This medication could be used together with other medications and diet and exercise to improve blood sugar levels in adults with type 2 diabetes. It works by increasing the amount of certain natural substances such as Incretin (Incretin is a hormone that raises insulin levels when blood sugar is high (especially after a meal) and decreases the amount of sugar made by the body).

Tradjenta does not help treating type 1 diabetes.

Doctor's prescription is required to use this medicine.

Always take Tradjenta (Linagliptin) as directed by your physician.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Ask your doctor if you have any questions.

Tradjenta (Linagliptin) comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take Tradjenta at around the same time every day. Do not stop taking this medication without talking to your doctor.

Do not take more or less of it or take it more often than prescribed by your doctor.

Always take Tradjenta (Linagliptin) exactly as directed by your doctor.

Before using Tradjenta, tell your doctor or pharmacist if you are allergic to it or any other medications. Tell your doctor or pharmacist about your medical history. Tell your doctor about all the other prescription and nonprescription medications you are taking.

Do not use Tradjenta if you:

• ever had a severe allergic reaction to linagliptin (breathing problems, swelling, severe skin rash); or

• have diabetic ketoacidosis (call your doctor for treatment).

• have type 1 diabetes.

To make sure Tradjenta is safe for you, tell your doctor if you have ever had:

• heart problems;

• kidney disease;

• pancreatitis;

• high triglycerides (a type of fat in the blood);

• gallstones;

• alcoholism; or

• if you are using insulin, or taking other oral diabetes medication.

Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking linagliptin, call your doctor.

Tradjenta is not approved for use by anyone younger than 18 years old.

NOTE: This medicine is only for you. Do not share this medicine with others.

Contact your doctor if you experience these side effects and they are severe or bothersome.

• Back pain
• Cough
• Diarrhea
• Headache
• Sore throat
• Stuffy or runny nose

Contact with your doctor as soon as possible if any of the following side effects occur:

• Mouth sores
• Skin rash
• Symptoms of low blood sugar (e.g., headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, and feeling jittery)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• Signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
• Symptoms of a serious allergic reaction (such as swelling of the face, lips, tongue, or throat; skin rash; hives; or difficulty breathing)
• Symptoms of pancreatitis (e.g., prolonged, severe abdominal pain with or without vomiting)

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What happens if I miss a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What happens if I overdose?

In case of an overdose, seek emergency medical attention or call the Poison Help line.

Where should I keep my medicine?

Keep out of reach of children.

Store the medicine at room temperature.

Throw away any unused medicine after the expiration date.

What should I avoid while taking this medication?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.