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What is Trelegy Ellipta (fluticasone/umeclidinium/vilanterol)?

Trelegy Ellipta is a bronchodilator combination medicine used to relax the muscles in the airways and improve breathing in patients with chronic obstructive pulmonary disease (COPD). This inhalation medicine is also used to treat symptoms of asthma in adults. With proper use, Trelegy Ellipta can improve symptoms such as wheezing, chest tightness, and shortness of breath. This medication contains a combination of fluticasone, umeclidinium, and vilanterol. Trelegy Ellipta is not to be used as an emergency quick-relief inhaler for asthma or bronchospasm attacks.

Use Trelegy Ellipta exactly as directed by your healthcare provider Refer to the directions on your prescription label and medication guides.

  • Prepare the inhaler for use by opening the cover
  • Fully exhale, then place the mouthpiece to your lips
  • Take a deep inhalation through the mouth
  • Do not inhale through your nose
  • Remove the inhaler
  • Hold your breath for four seconds or a comfortable duration
  • Exhale slowly
  • Close the inhaler and store it away from moisture, heat, and light
  • Rinse your mouth with water (do not swallow the water)

Cautions

Trelegy Ellipta may be unsafe if you have the following health conditions:

  • Hyperthyroidism or hypothyroidism 
  • Coronary artery disease
  • History of epileptic seizures
  • Osteoporosis (bone loss)
  • Diabetes
  • High blood pressure (hypertension)
  • Glaucoma or cataracts

Inform your doctor if you are taking the following medications:

  • Medicine for Parkinson’s disease
  • Cold or allergy medication
  • Antifungal or antiviral medicine
  • Bronchodilators like salbutamol ipratropium, and glycopyrronium
  • Medication for depression, anxiety, and other or mood disorders

Side Effects

Trelegy Ellipta side effects may include:

  • Sharp or dull throbbing sensations in the head
  • Nausea or vomiting
  • Mouth pain
  • Cold symptoms (runny nose, sore throat, and cough)
  • Joint pain
  • Mouth sores

Report serious side effects to your physician immediately. Serious side effects of Trelegy Ellipta may include:

  • Wheezing or breathing problems
  • White patches or sores in the mouth (thrush)
  • Blurred vision
  • Symptoms of low potassium, including fatigue and fast heartbeats
  • Tremors and involuntary shaking
  • High blood sugar (increased urination and weight loss)
  • Pain during urination or difficultly emptying the bladder
  • Chest tightness

FAQs

What should I avoid while using Trelegy Ellipta?

Do not combine Trelegy Ellipta with another inhaled bronchodilator medication unless specifically instructed by your doctor. Medicines that contain salmeterol, indacaterol, or formoterol may interact with Trelegy Ellipta and lead to adverse symptoms or unpredictable side effects. Also avoid being near those infected with chickenpox or measles. These conditions can potentially be fatal in those using any medication that contains fluticasone, such as Trelegy Ellipta.

What should I do if I miss a dose of Trelegy Ellipta?

Do not take more than 1 inhalation of Trelegy Ellipta per day unless your doctor specifically directs you to do so. If you miss a dose, skip the missed dose if it is near the time of your next dose. Overdosing can lead to severe symptoms, including chest pain, an accelerated heart rate, shakiness, and shortness of breath. See your doctor if you have taken too many inhalations of Trelegy Ellipta.

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