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Uloric (Febuxostat) belongs to a class of medications called xanthine oxidase inhibitors. Uloric (Febuxostat) is prescribed to treat gout in adults who were not treated successfully with or when they cannot take another medication called allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints and causes sudden attacks of redness, swelling, pain, and heat in one or more joints. This medication works by reducing the production of uric acid and controlling the uric acid levels from getting high in patients with gout.

Doctor's prescription is required to use this medicine.

Always take Uloric (Febuxostat) as directed by your physician.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Ask your doctor if you have any questions.

Uloric (Febuxostat) comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take Uloric at around the same time every day. Do not stop taking this medication without talking to your doctor.

Do not take more or less of it or take it more often than prescribed by your doctor.


Always take Uloric (Febuxostat) exactly as directed by your doctor.

Before using Uloric, tell your doctor or pharmacist if you are allergic to it or any other medications. Tell your doctor or pharmacist about your medical history. Tell your doctor about all the other prescription and nonprescription medications you are taking.

Febuxostat may increase your risk of serious or fatal heart problems. Talk with your doctor about the risks and benefits of this medicine.

Do not use Uloric if you are allergic to febuxostat, or if you also use azathioprine and/or mercaptopurine. Your doctor will probably tell you not to take febuxostat if you are taking one or more of these medications.

To make sure Uloric is safe for you, tell your doctor if you have ever had:

• heart problems;

• a heart attack or stroke;

• liver or kidney disease;

• cancer;

• Lesch-Nyhan syndrome; or

• an organ transplant (kidney, liver, lung, heart).

Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking febuxostat, call your doctor.

Your gout may flare up when you are first taking this medicine. Do not stop taking this medicine, even if you have a flare. Your doctor or health care professional may give you another medicine to help treat the gout pain.

NOTE: This medicine is only for you. Do not share this medicine with others.

Side Effects

Side effects that you should report to your doctor or health care professional as soon as possible:

-Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-Breathing problems
-Chest pain or chest tightness
-Fast, irregular heartbeat
-Feeling faint or lightheaded
-Fever with rash, swollen lymph nodes, or swelling of the face
-Redness, blistering, peeling or loosening of the skin, including inside the mouth
-Signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
-Signs and symptoms of a stroke like changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-Changes in appetite
-Joint pain
-Nausea, vomiting
-Upset stomach

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.



What happens if I miss a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What happens if I overdose?

In case of an overdose, seek emergency medical attention or call the Poison Help line.

Where should I keep my medicine?

Keep out of reach of children.

Store the medicine at room temperature. Protect from light and moisture.

Throw away any unused medicine after the expiration date.

What should I avoid while taking this medication?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.


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